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KMID : 0363219750130040257
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Korean Journal of Dermatology
1975 Volume.13 No. 4 p.257 ~ p.262
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Immunotherapy of Warts with DNCB
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Abstract
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Fifty-one cases of various warts were treated with 1-chloro-2, 4-dinitrobenzene (DNCB), and divided these warts into two groups by the method of treatment. The first group wasIreated by challenge on normal skin after sensitization and the second group was treated by challenge on wart lesion after sensitization. The number of first group was 27 consisted of 13 of Yerruca vulgaris, 12 of verruca plans. and 2 of oondyloma acuminatuna.´~The number of second group was 24 consisted of 10 of verruca vulgaris, 11 of verruca Plana and 3 of verruca plantaris.
The results are summarized as follows;
1. Thirty-one of all 51 cases (60.7%) were cured.
2. Fifteen of 27 cases (55.5%) were cured in first group.
3. Sixteen of 24 cases (66.6 % ) were cured in second group.
4. All 3 cases of verruca plantaris were cured in second group.
5. Eight cases were cured only by sensitization and consisted of 6 of verruca, plana and 2 of verruca vulgaris.
6. There was no significant difference in cure rates of warts between the group within 2 years of duration and the group over 2 years of duration.
7. There were no severe adverse reactions.
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